Ovarian Rejuvenation & PRP Therapy
Ovarian Rejuvenation using Platelet-Rich Plasma (PRP) is a cutting-edge regenerative treatment designed to enhance ovarian function, improve egg quality, and increase the chances of natural or assisted conception. By harnessing the body's own growth factors, PRP stimulates dormant follicles and supports ovarian tissue repair — offering new hope to women with diminished ovarian reserve or premature ovarian insufficiency.
What is Ovarian PRP?
Platelet-Rich Plasma (PRP) is derived from your own blood. A small sample is processed to concentrate the platelets and growth factors, which are then injected directly into the ovarian tissue. These growth factors promote cellular repair, stimulate folliculogenesis, and may awaken dormant primordial follicles — potentially restoring or improving ovarian activity.
The Procedure
Step-by-Step Process
- Blood Draw: A small volume of blood is collected from your arm
- Centrifugation: The blood is spun to isolate the platelet-rich plasma layer
- Ultrasound-Guided Injection: PRP is injected into the ovaries under transvaginal ultrasound guidance
- Monitoring: Ovarian response is tracked over 4–8 weeks with serial ultrasound and hormonal blood tests
The procedure is minimally invasive, typically performed under mild sedation, and takes approximately 30–45 minutes.
Benefits of Ovarian Rejuvenation with PRP
- Improved ovarian reserve (AMH levels) in select patients
- Better egg quality and higher follicle count for IVF cycles
- Potential restoration of menstrual cycles in early premature ovarian insufficiency
- Natural, autologous treatment — uses your own blood, no foreign substances
- Can be combined with IVF or natural conception attempts
- Minimal downtime and low complication risk
Ideal Candidates
- Women with low ovarian reserve (low AMH, high FSH)
- Poor responders to ovarian stimulation in previous IVF cycles
- Early premature ovarian insufficiency (POI) with residual follicular activity
- Women wishing to delay menopause or improve hormonal balance
- Those seeking natural fertility enhancement before pursuing assisted reproduction
Pre- and Post-Procedure Care
Pre-Procedure: Baseline hormonal testing (AMH, FSH, LH, estradiol) and an antral follicle count ultrasound are required. Avoid anti-inflammatory medications (aspirin, ibuprofen) for 5–7 days prior to the procedure.
Post-Procedure: Mild pelvic discomfort may occur for 1–2 days. Avoid strenuous activity for 48 hours. Follow-up hormonal and ultrasound assessments are scheduled at 4, 8, and 12 weeks to evaluate ovarian response.
Testimonials
"My AMH had been very low for years. After ovarian PRP with Dr. Unnati, my levels improved and I conceived naturally within four months. Truly life-changing." – Priya M., 36
"I was told IVF wouldn't work for me due to poor ovarian reserve. After PRP ovarian rejuvenation, my next IVF cycle retrieved three healthy eggs. We have a baby now." – Sunita R., 38
Frequently Asked Questions
How many PRP sessions are needed?
Most patients receive one to two sessions. The response is assessed after the first session before deciding on repeat treatment.
How soon can I see results?
Ovarian response typically begins within 4–8 weeks. Hormonal markers (AMH, FSH) and ultrasound follicle counts are used to monitor progress.
Is the procedure painful?
The injection is performed under sedation or local anaesthesia, making it well-tolerated. Mild cramping post-procedure is normal and resolves within 1–2 days.
Is ovarian PRP experimental?
Ovarian PRP is an emerging, evidence-supported treatment. While not yet standard protocol, growing clinical data shows meaningful improvements in ovarian reserve parameters, particularly in poor responders.
Can it be combined with IVF?
Yes. Many patients undergo PRP ovarian rejuvenation 4–8 weeks before an IVF stimulation cycle to optimise egg yield and quality.
Contact Dr. Unnati Mamtora
Speak with Dr. Unnati to find out if ovarian rejuvenation with PRP is right for your fertility journey.
+91 9930040177
Contact Person: Dr. Unnati Mamtora